1 dez. Metoclopramida, Tropisetron, Granisetron e Dexametasona. JUSTIFICATIVA E .. tratamento antiemético efetivo superam os dólares. com a diretriz foram prescrição de doses mais elevadas de dexametasona e . antiemético mais apropriado para cada agente antineoplásico isoladamente. Objetivo: evaluar el efecto profiláctico antiemético de la combinación dexametasona – metoclopramida en pacientes llevados a procedimientos.

Author: Munris Zulmaran
Country: Belize
Language: English (Spanish)
Genre: Science
Published (Last): 25 April 2004
Pages: 484
PDF File Size: 9.89 Mb
ePub File Size: 2.13 Mb
ISBN: 798-3-63296-712-4
Downloads: 94523
Price: Free* [*Free Regsitration Required]
Uploader: Voodookree

We do not intend to define the clinical practice in our country in absolute terms, but our results are consistent with literature data, and altogether demonstrate that much can be done to bring the anyiemetico practice closer to evidence-based medicine.

A droga mais frequentemente prescrita em dose inadequada foi a dexametasona. J Manag Care Pharm.

Evidence-based management of postoperative nausea and vomiting: Educational efforts should focus more intensely on the management of chemotherapy regimens with low and moderate emetogenic potential. Much of the stigma related to malignant neoplasms is due to the side effects of the treatment, particularly nausea and uncontrollable vomiting.

Intravenous ondansetron in established postoperative emesis in children. Improving physician adherence to clinical practice guidelines: The guideline used to assess the appropriateness of the prescriptions was the recommendation defined by ASCO in Dexamethasone for the prevention of postoperative nausea and vomiting: Table 3 Correlation of factors and appropriateness of the Brazilian Protocol and the American Society of Clinical Oncology protocol – univariate and multivariate analysis.

A factorial trial of six interventions for the prevention of postoperative nausea and vomiting. Br J Anaesth ; Recibido el 24 de junio, Dexamethasone is useful as prophylaxis for postoperative nausea and vomiting PONV. Barriers to guidelines adherence. The nausea and vomiting control depends on several factors, with emphasis on the underlying disease involvement of the gastrointestinal tractthe classes of chemotherapeutic agents and the individual predisposition of each patient.


Evaluations were made until discharge from the PACU and included presence of PONV, degree desametasona sedation, and other potential adverse effects of the study drugs.

Esto es posiblemente por la baja incidencia global de los efectos adversos con estas drogas. A idade mediana dos pacientes foi 56 anos 19 a 89 anos. Evaluation of new antiemetic agents and definition of antineoplastic agent emetogenicity—state of the art.

Perineal pruritus after i. Further studies are needed to define dexametaasona duration of this effect of dexamethasone. The only variable that tended to a significant association with adherence to the emesis protocol in multivariate analysis was high emetogenic potential chemotherapy.

Journal List Einstein Sao Paulo v. National Center for Biotechnology InformationU.

There was a problem providing the content you requested

Can J Anaesth ; Proposal for classifying the acute emetogenicity of cancer chemotherapy. The main disagreements with the directive were the prescription of higher doses of dexamethasone and excessive use of 5-HT3 antagonist for low risk emetogenic chemotherapy regimens.

The creation of incentive mechanisms, and checking adherence to protocols can be strategies for continuous improvement in health care. Perhaps the development of a computer generated reminder may improve the adherence to guidelines. For this purpose, cancer and palliative care organizations worldwide designed guidelines to indicate the most appropriate antiemetic regimen 267 for each antineoplastic agent, alone or in combination, and thereby facilitate the management of cancer patients, based on the best scientific evidence.

This study has limitations because this was a retrospective analysis based on the experience of a single institution. Guideline adherence rates generally also vary within each medical specialty. Se registraron los efectos adversos tales como cefalea, mareos, signos extrapiramidales y ardor o prurito perineal.


ANTIEMÉTICO – Definition and synonyms of antiemético in the Spanish dictionary

Can J Anesth ; To optimize the management of these side effects, several studies are investigating the triggering mechanisms, the emetogenic potential of each neoplastic agent, and the best strategy for the prevention of emesis. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

General data was similar for the 3 groups. Antiemetic prophylaxis and frequency of chemotherapy-induced nausea and vomiting in palliative first-line treatment of colorectal cancer patients: Author information Article notes Copyright and License information Disclaimer.

Meaning of “antiemético” in the Spanish dictionary

Postoperative nausea and vomiting. Author information Copyright and License information Disclaimer. Dexametasonaa Mar 26; Accepted Apr Open in a separate window. The medication most commonly prescribed in inadequate doses was dexamethasone. J Clin Anesth ; Table 1 Characteristics of patients and treatments. Dexamethasone; Droperidol; Ondansetron; Postoperative nausea and vomiting.

A simplified risk score for predicting postoperative nausea and vomiting: Adherence to the antiemetic prophylaxis guidelines of the American Society of Clinical Oncology was low in the first cycle of antineoplastic chemotherapy. The following variables were investigated with respect to adherence to the guideline: Other variables considered significant in the univariate analysis were not determinant of guideline adherence or non-adherence after the multivariate analysis Table 3.