ALIMTA PACKAGE INSERT PDF

ALIMTA (pemetrexed for injection) [package insert]. Indianapolis, IN: Eli Lilly and Company; Langer CJ, et al. Lancet Oncol. ;17(11) Learn how ALIMTA may help treat advanced nonsquamous non-small cell lung cancer. ALIMTA and carboplatin (carbo) is approved by the FDA to be used with an the FDA in combination with carboplatin (another chemotherapy drug) and. Read all of this leaflet carefully before you start receiving this medicine because it contains important information for you. -. Keep this leaflet. You may need to.

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Tell your healthcare provider right away if you have a decrease in amount of urine.

ALIMTA® (pemetrexed): Storage of Unreconstituted Vials

Adverse reactions observed in pediatric patients studied were similar to those observed in adults. For more information, ask your healthcare provider or pharmacist. Overall response rate a ORR: ALIMTA is contraindicated in patients who have a history of severe hypersensitivity reaction to pemetrexed.

Advise females of reproductive potential to use effective contraception during treatment with ALIMTA and for 6 months after the final dose. You are encouraged to report negative side effects of prescription drugs to the FDA.

NCCN makes no warranties of any kind whatsoever regarding their content, use, or application and disclaims any responsibility for their application or use in any way. Your healthcare provider will prescribe a medicine called a corticosteroid for you to take 2 times a day for 3 days, beginning the day before each treatment with ALIMTA.

Continued approval for this indication may be contingent upon verification and description of clinical benefit in the confirmatory trials. Tell your healthcare provider right away if you get any new or worsening symptoms of shortness of breath, cough, or fever. Indications and Important Safety Information.

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ALIMTA® (Pemetrexed) and Pharmacokinetics

Go to data for additional indications. ALIMTA is indicated as a single agent for the maintenance treatment of patients with locally advanced or metastatic nonsquamous non-small cell lung cancer NSCLC whose disease has not progressed after four cycles of platinum-based first-line chemotherapy. It is very important to take folic acid by mouth and receive vitamin B 12 injections from your healthcare provider during your treatment with ALIMTA to lower your risk of harmful side effects.

Tell your healthcare provider right away if you develop blisters, skin sores, skin peeling, or painful sores, or ulcers in your mouth, nose, throat or genital area. Accessed June 27, Severe vomiting or diarrhea can lead to loss of fluids dehydration which may cause kidney problems to become worse. If you are allergic to pemetrexed, tell your doctor because you should not receive it.

Males of Reproductive Potential: Tell your healthcare provider right away if you have any signs of infection, fever, bleeding, or severe tiredness during your treatment with ALIMTA.

Like cisplatin, carboplatin contains platinum. The risk of myelosuppression is increased in patients who do not receive vitamin supplementation. It is not known if these effects are reversible. Based on high-level evidence alimga, randomized controlled trials and there is uniform NCCN consensus inzert the intervention is appropriate.

Withhold ALIMTA for acute onset of new or progressive unexplained pulmonary symptoms such as dyspnea, cough, or fever pending diagnostic evaluation. Ibuprofen increases exposure AUC of pemetrexed.

ALIMTA® (pemetrexed for injection) | Official healthcare professionals site

Talk to your healthcare provider if this is a concern for you. The infusion is given over 10 minutes. Radiation recall is a skin reaction that can happen in people who have received radiation treatment in the past and are treated with ALIMTA.

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ALIMTA is indicated, in combination with cisplatin, for the initial treatment of patients with malignant pleural mesothelioma MPM whose disease is unresectable or who are otherwise not candidates for curative surgery. This indication is approved under accelerated approval based on tumor response rate and progression-free survival.

To view the most recent and complete version of the guidelines, go pakage to NCCN. Tell your healthcare provider about all of the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

Langer CJ, et al. Advise males with female partners of reproductive potential to use effective contraception during treatment with ALIMTA and for 3 months after the final dose.

If concomitant ibuprofen use cannot be avoided, monitor patients more frequently for ALIMTA adverse reactions, including myelosuppression, renal, and gastrointestinal toxicity. Low blood cell counts. Low blood cell counts can be severe, including alimtaa white blood cell counts neutropenialow platelet counts thrombocytopeniaand low red blood cell counts anemia.

Nisert a inseet blood count at the beginning of each cycle. ALIMTA can cause severe myelosuppression resulting in a requirement for transfusions and which may lead to neutropenic infection.

Tell your healthcare provider if you have any side effect that bothers you or that does not go away. Hold on longer to what matters most. Based on Kaplan-Meier estimation. Tell your healthcare provider if you have kidney problems and take a medicine that contains ibuprofen.

Scagliotti GV, et al. Advise pregnant women of the potential risk to the fetus.